The government has just hours to intervene to stop Doncaster Sheffield Airport from closing, ministers have been told.
Owner Peel said last month operations would wind down from the end of October as it was not financially viable.
Labour MPs accused the government of not doing enough and said ministers had not met with South Yorkshire leaders.
Transport minister Katherine Fletcher said the government had held talks with Peel multiple times.
Stephanie Peacock, Labour MP for Barnsley East, told the Commons the airport was a valuable regional economic asset and "thousands of jobs" depended on it.
"Despite Peel Group announcing its closure, local leaders have made every effort to work with the group and to work with the government to secure the airport's future," she said.
Speaking on Monday evening, she said investors needed certainty in the next 24 hours.